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HCV quasi-species

Vikas Bhushan (Admin0) hace 13 años actualizado hace 13 años 0
Know that RNA-polymerase in HCV lacks 3' --> 5' exonuclease =======> HCV is genetically unstable due to lack of 3' -->5' exonuclease proofreading activity and an envelope glycoprotein with a hypervariable region prone to frequent mutation